Turner syndrome and growth hormone therapy: a review on growth response
نویسندگان
چکیده
منابع مشابه
Turner syndrome and growth hormone therapy: a review on growth response
Results The mean age of initiation of therapy was 11.5 ± 3.4 and 55.0% were started after the age of 12 years. The mean height standard deviation score (SDS) increased from -3.84 (±0.94) SD at study entry to -3.47 (±0.97) SD at the end of the first year. This improvement was seen with subsequent year of treatment, though the degree of change in height SDS reduced with time. Age of initiation of...
متن کاملGrowth Hormone in Turner Syndrome
We studied the adult height (AH) outcome, and factors likely to influence it, in Turner Syndrome (TS) girls treated with growth hormone (GH). A total of 25 TS girls treated with GH were compared with 10 TS girls not treated with GH. The percentage of girls who achieved normal third percentile was determined. Projected AH (PAH) was calculated according to height standard deviation score (HSDS) a...
متن کاملGrowth hormone therapy in patients with Turner syndrome.
This article summarizes the published data on final height after growth-promoting therapy in Turner syndrome. Using growth hormone (GH) doses ranging between 0.5 and 1.2 IU/kg/week, final height after therapy is improved by 1.5-9.3 cm [final height after therapy vs. projected adult height (PAH)] within various studies. There is no obvious GH dose-response relationship, but a better estimated be...
متن کاملHeight in Turner syndrome: does growth hormone therapy have impact?
Sir Short stature is a cardinal feature of Turner syndrome. We examined height outcome and its relation to growth hormone therapy in Irish girls with Turner syndrome. In those with Turner syndrome (TS), the adult stature is an average 20 cm shorter than the general population 1 . By 15 years of age, the average height of an untreated girl with TS is equivalent to that of only a 9.5-year-old gir...
متن کاملResponse to three years of growth hormone therapy in girls with Turner syndrome
PURPOSE Short stature is the most common finding in patients with Turner syndrome. Improving the final adult height in these patients is a challenge both for the patients and physicians. We investigated the clinical response of patients to growth hormone treatment for height improvement over the period of three years. METHODS Review of medical records from 27 patients with Turner syndrome tre...
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ژورنال
عنوان ژورنال: International Journal of Pediatric Endocrinology
سال: 2015
ISSN: 1687-9856
DOI: 10.1186/1687-9856-2015-s1-p37